Certainly. If you think you've got taken too much codeine linctus, search for urgent clinical interest by contacting your GP or going to your clinic's accident and unexpected emergency. Overdosing with codeine may cause critical breathing troubles and may end up in Loss of life if taken in pretty large doses.
Lifetime-threatening breathing issues (respiratory melancholy). PROMETHAZINE WITH CODEINE ORAL Answer may cause respiratory troubles (respiratory melancholy) which can take place at any time in the course of remedy and may lead to Loss of life. Your hazard of respiration difficulties is biggest when you initial begin having PROMETHAZINE WITH CODEINE ORAL Remedy, are getting other medicines that might cause breathing problems, have specified lung issues, are elderly or have specified other health conditions.
Codeine and its active metabolite, morphine, are present in breast milk. A look for of your clinical literature1-19 for pertinent data concerning codeine use through lactation uncovered many reports of respiratory melancholy and sedation, including just one toddler death, particularly in moms who've the CYP2D6ultra-swift metabolizer genotype.
The next serious adverse reactions are described, or described in bigger detail, in other sections:
Individuals need to be recommended to evaluate Promethazine HCl Oral Remedy having an accurate measuring product. A home teaspoon will not be an correct measuring product and could lead on to overdosage, specially when a half a teaspoon is measured.
Codeine may well induce miosis, even in complete darkness. Pinpoint pupils are a sign of opioid overdose but are certainly not pathognomonic (eg., pontine lesions of hemorrhagic or ischemic origin could create similar findings). Marked mydriasis as read more opposed to miosis may be found with hypoxia in overdose cases [see
No - you should not acquire this medication if Expecting or looking to get pregnant. You should seek out GP information should you involve treatment for the dry more info cough.
This drugs may perhaps induce some individuals to become dizzy, lightheaded, drowsy, or significantly less inform than They may be Commonly. Although taken at bedtime, it could bring about a get more info number of people to come to feel drowsy or a lot less inform on arising.
The concomitant use of opioids with other medicines that have an impact on the serotonergic neurotransmitter program has resulted in serotonin syndrome.
Just after initiation of procedure more info in youngsters or Older people, dosage should be altered into the least amount ample To alleviate signs or symptoms.
The Lively ingredient while in the linctus is Codeine. Codeine is from your household of medicines known as opioids, and together with the effect on lessening coughing, it can even be utilized like a discomfort killer.
In women with typical codeine metabolism, the level of codeine secreted into breast milk is reduced and dose-dependent.
The codeine and promethazine in Promethazine with Codeine Oral Answer may possibly increase the frequency of seizures in patients with seizure Issues, and should enhance the danger of seizures transpiring in other scientific settings connected to seizures.
Should you have established that a codeine-or tramadol-containing solution is appropriate for an adolescent patient, counsel mothers and fathers and caregivers get more info on how to acknowledge the signs of opioid toxicity, and advise them to halt providing the adolescent codeine or tramadol and look for medical notice promptly if their adolescent is exhibiting these indications.